engleski

Salmonella enterica arthritis in a rheumatoid arthritis patient under anti-tumor necrosis factor therapy

Anti-tumor necrosis factor (TNF) monoclonal antibodies have become an invaluable treatment against chronic inflammatory diseases such as rheumatoid arthritis (RA). However, due to increased risk of opportunistic infections, patients receiving anti-TNF therapy should be closely monitored for serious infections. Here we describe a case of acute Salmonella Enteritidis infection of a joint arthroplasty that previously was functioning well, in a patient receiving infliximab treatment for RA. After prolonged antimicrobial chemotherapy and interrupted infliximab treatment, reimplantation of a new prosthesis was successfuly performed two years after Salmonella septic arthritis. Therefore, because of possibility of extraintestinal salmonellosis, screening for fecal colonization could be advisable in patients undergoing anti-TNF treatment. Moreover, we emphasize the importance of appropriate counseling of these patients concerning food hygiene.

anti-TNF treatment; knee infection; Salmonella Enteritidis

The Association of Surgeons in Jamaica Conference.