engleski

Biologically relevant theory about radiofrequency radiation impact on cell redox processes

Over the years due to rapid technological progress, radiation from man-made sources exceeded those of natural origin. There is a general concern regarding growing number of appliances that use radiofrequency (RF) radiation with particular emphasis on mobile communication system. Since non-thermal biological effects of RF radiation are still uncertain as well as their mechanisms, laboratory studies on tissues, cells and cell free system are of extraordinary importance in bioelectromagnetic research. We believe that such investigations play a supporting role in public risk assessment. Cellular systems with the potential for clear response to RF exposures should be used in those studies. It is known that organism is a complex electrochemical system where among many others, processes of oxidation and reduction regularly occur. During these reactions electrons are transferred from one molecule to another forming small amount of free radicals. Most important class among radicals is certainly presented by reactive oxygen species (ROS). Depending on concentration, ROS can have both beneficial and deleterious effects. Positive effects are connected with cell signalling, defence against infectious agents and mitogenic response. On the other hand, excessive production which overloads antioxidant defence mechanism leads to cellular damage with serious potential for disease development. ROS concentration increase within the cell caused by RF radiation seems to be biologically relevant hypotheses to give clear insight into the RF action at non-thermal level of radiation.

reactive oxygen species; radiofrequency (RF) radiation; antioxidant

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