Microstructural characterizations of different Mn- oxide nanoparticles used as models in toxicity studies (CROSBI ID 188089)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Gotić, Marijan ; Jurkin, Tanja ; Musić, Svetozar ; Unfried, Klaus ; Sydlik, Ulrich ; Bauer-Šegvić, Anamarija
engleski
Microstructural characterizations of different Mn- oxide nanoparticles used as models in toxicity studies
Mn-oxide microstructures were investigated by XRD, FT-IR, TEM, FE SEM and EDS techniques. The oxidation of the aqueous solutions of manganese (II) chloride by hydrogen peroxide was employed to synthesize pure 20-30-nm pseudospherical hausmannite (Mn3O4) nanoparticles and manganite (γ-MnOOH) nanowires. The α-MnO2 nanotubes and nanorods were hydrothermally synthesized starting from a KMnO4 precursor, then modified with the addition of divalent metal cations Mn2+, Cu2+, Ni2+ and Fe2+. The modification with Mn2+ induced the transformation of α-MnO2 nanotube into 3D β- MnO2 (pyrolusite) prismatic nanoparticles, whereas the low-crystalline α-MnO2 nanorods were transformed into disc-like γ-MnO2 nanoparticles. The modification with Cu2+ and Ni2+ induced the structural transformation of α-MnO2 into a mixture of MnO2 polymorphs. The modification with Cu2+ decreased, whereas the modification with Ni2+ improved the crystallinity of MnO2. The modification with Fe2+ induced the structural transformation of α-MnO2 into γ-MnO2, a decrease in crystallinity and the segregation of α-Fe2O3 (hematite). Thus the modification of MnO2 with Fe2+ (Mn2+) divalent metal cations that can be oxidized into Fe3+ (Mn4+) by a KMnO4 precursor differs significantly in comparison with, in this case, non-oxidizable cations such as Cu2+ and Ni2+. On the other hand, the advantage that the modification of MnO2 with Mn2+ produces chemically identical compounds with different morphology can be used as a model system for toxicity studies. In this work the preliminary measurements of intracellular oxidative stress in epithelial cells induced by manganese oxide nanoparticles are reported.
manganese oxides; nanoparticles; microstructures; toxicity
EUCMOS XXXIEUCMOS XXXI ; Simion Aştilean, Austin J. Barnes, Vasile Chiş, Onuc Cozar (ur.).
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o izdanju
1044
2013.
248-254
objavljeno
0022-2860
10.1016/j.molstruc.2012.09.083