engleski

Adjustment of process conditions in seeded batch cooling crystallization

The influence of seed addition temperature, seeds surface area and seeds of different origin on the granulometric characteristics and polymorphism of glycine were examined. At sufficient surface seed area, regular and narrow crystal size distribution (CSD) was obtained. Differential scanning calorimetry (DSC) and X - ray diffraction (XRD) analysis were carried out for investigations of polymorphism. Differences in seed size and seed mass couple influenced the granulometric properties but didn’t cause changes in polymorphic structure. Four experiments with different origin seeds were carried out at optimal process conditions determined by preliminary experiments. Different seed origin caused differences in supersaturation level and CSD but structure of obtained crystals remained the same as loaded seed.

glycine ; granulometric properties ; polymorphism ; seeding crystallization

Special Issue: Industrial Crystallization.