Morphology, mechanical properties and bioactivity of PCL coated hydroxyapatite scaffold derived from cuttlefish bone (CROSBI ID 598290)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Milovac, Dajana ; Gallego Ferrer, Gloria ; Ivanković, Marica ; Ivanković, Hrvoje
engleski
Morphology, mechanical properties and bioactivity of PCL coated hydroxyapatite scaffold derived from cuttlefish bone
Mechanical properties of highly porous hydroxyapatite (HA) scaffold derived from aragonitic cuttlefish bone were improved by coating with 20wt. % solution of polycaprolactone (PCL).The phase composition and microstructure of the scaffold were examined by XRD, TGA, FTIR and SEM. Bioactivity was tested by immersion in HBSS and mechanical tests were performed at compression. SEM observation of the HA/PCL scaffold revealed a thin film of PCL covering the original architecture of cuttlefish bone. Bioactivity test showed the precipitation of calcium deficient HA particles with molar ratio (Ca/P = 1.58) in both HA and HA/PCL scaffolds. A novel HA/PCL bioactive scaffold with enhanced mechanical properties has been prepared preserving the natural well interconnected porous structure of cuttlefish bone. The scaffold could be suitable for cell attachment, proliferation and differentiation and could be used in bone tissue engineering applications [1]. References: [1] B.S. Kim, J.S. Kim, H.M. Sung, H.K. You, J. Lee, J Biomed Mater Res A.(2012) 100(7):1673-9
hydroxyapatite/polycaprolactone scaffold; morphology; mechanical properties; bioactivity
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Podaci o prilogu
P6-47-x.
2013.
objavljeno
Podaci o matičnoj publikaciji
European Polymer Congress (EPF 2013), Book of Abstracts
Podaci o skupu
European Polymer Congress (EPF 2013)
poster
16.06.2013-21.06.2013
Pisa, Italija