hrvatski

Epidemija hemoragijske vrućice s bubrežnim sindromom u Hrvatskoj 2012. godine / Outbreak of haemorrhagic fever with renal syndrome in Croatia during 2012

Croatia is a well-known endemic focus for hantaviruses that cause haemorrhagic fever with renal syndrome (HFRS), representing an emerging public health problem in Europe. We describe an unusual outbreak of HFRS in Croatia during 2012, in a new endemic focus of hantavirus, partially linked to the 2012 Snow Queen Trophy slalom race, which is held on Mt. Medvednica, otherwise popular resort. 154 people were diagnosed with HFRS in Croatia during the 2012 outbreak, of whom 95 (61.7%) were hospitalized at the University Hospital for Infectious Diseases in Zagreb. Out of 95 patients, 66 (69.5%) acquired the infection on Mt. Medvednica. Clinical and laboratory data of 85 patients with serologically confirmed hantavirus infection were described, with 81 (95.3%) cases of Puumala and 4 (4.7%) cases of Dobrava virus confirmed. Among all patients, 68 (79%) were male, mean age was 40 (range 22–71) years. Patients were hospitalized on day 5 (IQR 4–6) from the onset of disease and hospitalization lasted for an average of 11 (range 3–28) days. A mild form of the disease was present in 65 (76.5%) patients, moderate in 16 (18.8%), and severe in 4 (4.7%) patients. Fever (100%), chills / shivering (94.1%), headache (92.9%), myalgia and back pain (75.3%) were the most common clinical manifestations. This epidemic is also significant because of the unusually early onset for Croatia (in January), which resulted in coincidence with the flu outbreak. Considering the overlapping of clinical symptoms, probably part of patients were misdiagnosed as flu. The Mt. Medvednica environment could pose a serious public health risk with regard to hantavirus in the future because it is located in the immediate vicinity of the Croatian capital of Zagreb, towards which a quarter of the Croatian population gravitates.

DOBV; HFRS; Medvednica; PUUV

nije evidentirano

engleski

Epidemija hemoragijske vrućice s bubrežnim sindromom u Hrvatskoj 2012. godine / Outbreak of haemorrhagic fever with renal syndrome in Croatia during 2012

Croatia is a well-known endemic focus for hantaviruses that cause haemorrhagic fever with renal syndrome (HFRS), representing an emerging public health problem in Europe. We describe an unusual outbreak of HFRS in Croatia during 2012, in a new endemic focus of hantavirus, partially linked to the 2012 Snow Queen Trophy slalom race, which is held on Mt. Medvednica, otherwise popular resort. 154 people were diagnosed with HFRS in Croatia during the 2012 outbreak, of whom 95 (61.7%) were hospitalized at the University Hospital for Infectious Diseases in Zagreb. Out of 95 patients, 66 (69.5%) acquired the infection on Mt. Medvednica. Clinical and laboratory data of 85 patients with serologically confirmed hantavirus infection were described, with 81 (95.3%) cases of Puumala and 4 (4.7%) cases of Dobrava virus confirmed. Among all patients, 68 (79%) were male, mean age was 40 (range 22–71) years. Patients were hospitalized on day 5 (IQR 4–6) from the onset of disease and hospitalization lasted for an average of 11 (range 3–28) days. A mild form of the disease was present in 65 (76.5%) patients, moderate in 16 (18.8%), and severe in 4 (4.7%) patients. Fever (100%), chills / shivering (94.1%), headache (92.9%), myalgia and back pain (75.3%) were the most common clinical manifestations. This epidemic is also significant because of the unusually early onset for Croatia (in January), which resulted in coincidence with the flu outbreak. Considering the overlapping of clinical symptoms, probably part of patients were misdiagnosed as flu. The Mt. Medvednica environment could pose a serious public health risk with regard to hantavirus in the future because it is located in the immediate vicinity of the Croatian capital of Zagreb, towards which a quarter of the Croatian population gravitates.

DOBV; HFRS; Medvednica; PUUV

nije evidentirano