Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi

BMP-7 induced osteogenesis in partial calvarial bone defects and subcutaneous sites in rats (CROSBI ID 479981)

Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija

Zoričić, Sanja ; Marić, Ivana ; Bobinac, Dragica BMP-7 induced osteogenesis in partial calvarial bone defects and subcutaneous sites in rats // Calcified tissue international. Supplement / Avioli, LV (ur.). 2000. str. S93-S93

Podaci o odgovornosti

Zoričić, Sanja ; Marić, Ivana ; Bobinac, Dragica

engleski

BMP-7 induced osteogenesis in partial calvarial bone defects and subcutaneous sites in rats

The osteogenesis induced by rhBMP-7 bound to inactive bone residue (IRBR) implanted in rats have been studied at ectopic and orthotopic sites. IRBR with or without BMP-7 were implanted onto calvarial defects, onto intacted calvaria and subcutaneouslly in thoracic region of rats. Implants were harvested at day 7, 12 and 21 and analysed by histology, histochemistry, histomorphometry and immunohistochemistry. The results showed differences in initial cellular response between implants from different sites. At a subcutaneous sites BMP-7-reconstructed implants induced abundant cartilage on day 7. On the contrary, BMP-7 at calvarial sites induced direct bone formation. On day 21 all implants consisted mainly of bone. In both calvarial sites bone remodeling was active and lamellar bone was already formed. Implants from partial calvarial defect completely fused with the underlying bone. The results of histomorphometry showed more pronounced and rapid osteogenessis in both calvarial implants. In conclusion we suggest that BMP-7 induced different rate of osteogenesis at ectopic vs orthotopic sites.

bone morphogenetic proteins; osteogenesis; ectopic bone

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o prilogu

S93-S93.

2000.

nije evidentirano

objavljeno

Podaci o matičnoj publikaciji

Calcified tissue international. Supplement

Avioli, LV

New York (NY): Springer

0944-0747

Podaci o skupu

European Symposium on Calcified Tissues (27 ; 2000)

poster

06.05.2000-10.05.2000

Tampere, Finska

Povezanost rada

Temeljne medicinske znanosti