The influence of arecoline, physostigmine and lecithin on the passive avoidance aquisition in the nucleus basalis lesioned rats (CROSBI ID 604490)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | domaća recenzija
Podaci o odgovornosti
Simonić, Ante ; Župan, Gordana ; Atanacković, Dimitrije
engleski
The influence of arecoline, physostigmine and lecithin on the passive avoidance aquisition in the nucleus basalis lesioned rats
Approximately 70% cholinergic projections of the frontoparietal neocortex is derived from ACh neurons in substantia innominata/nucl1eus basalis (SI/NB). The purpose of this study was to examine: 1) the influence of SI/NB lesion on the passive avoidance acquisition in the rat, and 2) if arecoline (1 mg/kg i.p.), physostigmine (0, 1 mg/kg i.p.) and lecithine (250 mg i.p.) may reverse the memory deficit of lesioned rats. Bilateral SI/NB lesion significantly impaired the passive avoidance acquisition related to the control group and sham lesioned rats. Acquisition was significantly improved in arecoline-treated rats, while physostigmine or lecithine didn't influence it significantly.
nucleus basalis; arecoline; physostigmine; lecithine; passive avoidance; rat
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Podaci o prilogu
45-45.
1985.
objavljeno
Podaci o matičnoj publikaciji
Abstracts of Communications of 9th Congress of the Yugoslav Pharmacological Society and 4th Congress of the Yugoslav Toxicological Society /
Beograd: Savez društava fiziologa Jugoslavije
Podaci o skupu
9th Congress of the Yugoslav Pharmacological Society and 4th Congress of the Yugoslav Toxicological Society
poster
11.09.1985-14.09.1985
Beograd, Jugoslavija