Mass spectrometry based clinical proteomics (CROSBI ID 605069)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Starcevic, Antonio ; Cindrić, Mario ; Diminić, Janko ; Butorac, Ana ; Bačun-Družina, Višnja ; Gaćeša, Ranko ; Friganović, Maja
engleski
Mass spectrometry based clinical proteomics
Rapid sequencing of peptides using MALDI-TOF is still a challenge since it is considered as a critical capability in modern proteomics research. It is a tool of utmost importance for rapid identification of pathogenic cells, as well as for high throughput characterization of cell-based products in pharmaceutical and food processing industry. Coupling this technology with newly developed computer software it is possible to deliver new services capable of "one step" identification of target proteins in a microorganism or a cell. In order to achieve this goal, we propose a faster, cheaper, more selective and reproducible analytical method for the determination of amino acid sequence of peptides (triptic digests) by derivatisation with disulphonic acid (Patent protected technology of Ruđer Bošković Institute) coupled with novel software developed at Faculty of Food Technology and Biotechnology. Above mentioned methods applied to proteomic analyses could eventually be applied in clinical practice as fast, reliable and efficient tools for microorganism detection and identification.
Proteomics research ; rapid sequencing of peptides ; MALDI-TOF ; rapid identification of pathogenic cells ; computer software
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Podaci o prilogu
118-119.
2013.
objavljeno
Podaci o matičnoj publikaciji
Book of Abstracts
Kniewald, Zlatko
Zagreb: Akademija tehničkih znanosti Hrvatske (HATZ)
978-953-7076-2214
Podaci o skupu
2nd International Symposium “VERA JOHANIDES”
predavanje
10.05.2013-11.05.2013
Zagreb, Hrvatska