engleski

RENAL BIOPSY DATABASE FROM THE DEPARTMENT OF PATHOLOGY DUBRAVA UNIVERSITY HOSPITAL ZAGREB

Introduction and Aims: Renal biopsy database in the Department of Pathology, Dubrava University Hospital was created in 2003. The aim of the database is to accumulate computer-based pathologic data concerning all renal biopsy samples examined at the Department. With our database we can show the epidemiology of renal diseases diagnosed by kidney biopsy: incidence and trends in epidemiology. The aim of this study is to show incidence of some of the renal diseases that were diagnosed at our Department from 2003.-2010.. Methods: We have reviewed the database over a 7 years period and performed statistical analysis of our data including number of biopsies through years, patients gender, age, number of biopsies per patient, diagnoses and hospitals where the biopsy was performed. Results: During a 7 years period there were 2177 renal biopsies (1279 males ; 883 females, 15 donor kidneys, mean age 51 years). There were 1274 native renal biopsies and 888 renal transplant biopsies. Biopsies originate from 11 croatian hospitals and 1 hospiital from Bosnia and Herzegovina. The number of biopsies increased 15, 9 times in that period (from 34 biopsies in 2003. to 542 in 2010.). Among 1274 native renal biopsies, men were 1, 4 times more biopsied than women (M:F=734:540). Among them, glomerular diseases were the most frequent diagnosis (80%). The most common diagnose was IgA nephropathy, diagnosed in 223 cases followed by focal segmental glomerulosclerosis (FSGS) in 180 cases. Among 888 renal transplant biopsies men had 1, 3 times more biopsies then women, (M:F=546:342), mean age was 47, 4 years. Acute tubular injury was the most common disease diagnosed in 332 samples, followed by acute cellular rejection in 212 renal transplant biopsy samples. Conclusions: Primary glomerular diseases were 1, 6 times more frequent then secondary. Some diseases are more frequent in men then in women and vice versa. To our knowledge around 80% of renal biopsy samples from Croatia are examined in our department. Our results show the epidemiology of the renal diseases requiring biopsy in almost whole Croatia.

Renal biopsy; registry

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