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Quantitative Analysis of Troponin I Serum Values in Patients with Acute Cholecystitis (CROSBI ID 202877)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Babić, Žarko ; Bogdanović, Zoran ; Dorosulić, Zdravko ; Basha, Merita ; Krznarić, Željko ; Sjekavica, Ivo ; Kujundžić, Milan ; Tadić, Mario ; Banić, Marko ; Jagić, Vjekoslav et al. Quantitative Analysis of Troponin I Serum Values in Patients with Acute Cholecystitis // Collegium antropologicum, 36 (2012), 1; 145-150

Podaci o odgovornosti

Babić, Žarko ; Bogdanović, Zoran ; Dorosulić, Zdravko ; Basha, Merita ; Krznarić, Željko ; Sjekavica, Ivo ; Kujundžić, Milan ; Tadić, Mario ; Banić, Marko ; Jagić, Vjekoslav ; Marušić, Marinko

engleski

Quantitative Analysis of Troponin I Serum Values in Patients with Acute Cholecystitis

The diagnosis and staging of acute cholecystitis, upon a lot of diagnostic methods and some scoring systems, is still a great clinical problem. The aim of the study was to investigate if serum Troponin I is elevated in patients with acute cholecystitis. Following informed consent, 65 patients with clinical and laboratory signs of acute cholecystitis were enrolled. All patients had measured serum Troponin I level and an abdominal ultrasound was done before definitive treatment was performed. Increased serum Troponin I level was found in most patients with severe form of acute cholecystitis (p<0.00001). It reached sensitivity of 94.5% and specificity of 57.1% of this test. In multiple regression analysis Troponin I significantly correlated (p<0.05) with the serum aspartate aminotransferase (r=0.27), gamma- -glutamyl transferase (r=0.25) and gallbladder wall (>6 mm) thickness (r=0.58). Our study confirms that in most patients with severe and acute cholecystitis, serum Troponin I is increased. Troponin I level is in a lower range than it would be in patients with cardiac muscle damage or necrosis. Measuring serum Troponin I is a fast, reliable and widely performed test that could, with other routinely measured parameters, help in early diagnosis of the severe form of acute cholecystitis.

acute cholecystitis; Troponin Ic; staging

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Podaci o izdanju

36 (1)

2012.

145-150

objavljeno

0350-6134

Povezanost rada

Kliničke medicinske znanosti

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