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Important physiological features of the lactic acid bacterium employed in lactic acid production

One of the key characteristics of industrial bioprocesses is near maximum specific product formation rate and it can be attained as result of focused metabolic activity of employed microorganism under operational conditions. Most of the current knowledge about the metabolic activity of traditional industrial microorganisms - lactic acid bacteria includes relatively simple metabolic network based on carbohydrate catabolism and lactate production. However, recent investigations of metabolic flexibility of the lactic acid bacteria showed need for further investigation of their metabolic potential which can significantly improve efficiency of the industrial bioprocesses. Physiology of the lactic acid bacterium Lactobacillus coryniformis was investigated in a chemically defined medium containing glucose as main carbon and energy source. Batch cultivations were carried out at relatively low temperature and effect of dissolved oxygen and carbon dioxide concentration on bacterial growth was investigated. Limitation with carbon and energy source and accumulation of biomass was connected with D-lactic acid and other end-products formation.

bacterial physiology; lactic acid bacterium; bioprocess conditions; lactic acid production

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