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Membrane lateral domain structure involvment in scavenging of radicals (CROSBI ID 481101)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa

Schara, Milan ; Bratanič, Borut ; Žuvić-Butorac, Marta ; Nemec, Marjana ; Batista, Urška Membrane lateral domain structure involvment in scavenging of radicals // 3rd meeting of the slovenian biochemical society with international participation. Portorož, 1999. str. 86-x

Podaci o odgovornosti

Schara, Milan ; Bratanič, Borut ; Žuvić-Butorac, Marta ; Nemec, Marjana ; Batista, Urška

engleski

Membrane lateral domain structure involvment in scavenging of radicals

Membrane lateral domains have been verified by different experimental approaches, and the theoretical models fit the general ideas of the possible molecular organization. Electron paramagnetic resonance of the spin probe tagged cell membranes, renders valuable inforamtion on membrane in situ in cell suspensions and tissues. It was found that the domains structure is sensible system, which responds primarily via the domain population rearrangment, to the action of the extermnal stress. We tried to identfy the possile role of cell membrane domain structure on the scavenging of radicals, the spin probe, by which the domain structure was determined. The domain structure altrations induced by bilirubin haver been accompanied by the decrease of the reduction rate of the radicals.. In the proposed model, we assumed that the observed decrease of the fluid ordered membrane domain population is directly correlated with the decreased membrane permeability. Such effects have been observed in fibroblasts and neurons. It is our intention to describe some processes of cellular defense, where involvment of membrane domain structure might be supportive.

membrane; lateral domain structure; radicals; scavenging

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Podaci o prilogu

86-x.

1999.

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objavljeno

Podaci o matičnoj publikaciji

3rd meeting of the slovenian biochemical society with international participation

Portorož:

Podaci o skupu

3rd meeting of the slovenian biochemical society with international participation

pozvano predavanje

25.09.1999-29.09.1999

Portorož, Slovenija

Povezanost rada

Fizika