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izvor podataka: crosbi

Biliary atresia: the Croatian experience (CROSBI ID 617097)

Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija

Grizelj, Ruža ; Senečić-Čala, Irena ; Novak, Milivoj ; Batinica, Stipe ; Vuković, Jurica Biliary atresia: the Croatian experience // Journal of pediatric gastroenterology and nutrition. 2010. str. 164-165

Podaci o odgovornosti

Grizelj, Ruža ; Senečić-Čala, Irena ; Novak, Milivoj ; Batinica, Stipe ; Vuković, Jurica

engleski

Biliary atresia: the Croatian experience

Objectives and Study: This study objective was to deter- mine the outcomes of Croatian children with biliary atresia. Methods: Health records of infants born in Croatia between January 1, 1992 and December 31, 2006 who were diagnosed with biliary atresia and treated at a single university center were reviewed. Survival rates were calculated with the Kaplan-Meier method. Results: 29 patients with biliary atresia were identified. Incidence was 1 in 23 606 live births. The median age at Kasai operation was 66 days (range 22 – 192). Median fol- low-up was 2.65 years (range 0.2 – 14.3). Overall survival rates for the patients who underwent Kasai portoenterostomy, including those 6 (20%) who subsequently underwent liver transplantation were 75.6%. 5- and 10-year native liver survival rates were 61, 4% and 39, 8% respectively (median survival time was 7.88 years). Survival rates curves in two groups of patients according the biliary atresia phenotype (fetal or perinatal form) were divergent. Survival was 87.7 % in perinatal form, and 43.8 % in fetal form (Breslow chi square 8.082, P < 0.01). Conclusion: Overall survival rates of patients with biliary atresia in Croatia compares unfavorably with current international standards and they could be improved with earlier referral for liver transplantation. Results of Kasai operation (native liver survival rates) are very good in comparison with results reported elsewhere.

biliary atresia ; outcome ; epidemiology

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Podaci o prilogu

164-165.

2010.

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objavljeno

Podaci o matičnoj publikaciji

Journal of pediatric gastroenterology and nutrition

0277-2116

1536-4801

Podaci o skupu

43rd Annual Meeting of The European Society for Paediatric Gastroenterology, Hepatology and Nutrition

poster

09.06.2010-12.06.2010

Istanbul, Turska

Povezanost rada

Kliničke medicinske znanosti

Indeksiranost