Importance of changed tongue mucosa for Helicobacter pylori colonization (CROSBI ID 93770)
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Gall-Trošelj, Koraljka ; Jurak, Igor ; Mravak-Stipetić, Marinka ; Pavelić, Jasminka
engleski
Importance of changed tongue mucosa for Helicobacter pylori colonization
Helicobacter pylori is able to colonize gastric epithelia and cause chronic active gastritis, gastric and duodenal ulcers and presumably gastric malignancies (4). Attempts to identify the natural reservoir for this microorganism other than stomach have been unsuccessful for many years (15). Results published by Grubel et al. suggest that houseflies can harbor viable H. pylori on their bodies as well as in their intestinal tract, they are able to disseminate viable H. pylori in excreta, and may therefore present a potential reservoir and be a vector in transmission of bacteria (7). Based on an animal model, Yoshimatsu et al. concluded that H. pylori might be transmitted through a fecal-oral route from challenged to nonchallenged nude mice. After coercing challenged and nonchallenged animals fro two and four weeks, its presence was detected in 50% and 70% of mice, respectively. Most importantly, no transmission occurred in mice not exposed to feces of challenged mouse while sharing food and water in the same cage (26). Based on their resuts, the possibility of oral-oral transmission does not seem plausible.
Helicobacter pylori ; transmission ; oral cavity
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Temeljne medicinske znanosti