engleski

Identify pathogen organisms from a stream of RNA sequences

Metagenomics is an interesting new field of science focused on characterization of microbial communities from environmental samples. It is especially important as many organisms cannot be cultivated in a laboratory and therefore can reveal previously unknown species. This thesis presents a taxonomy- dependent alignment-based method for determining species present in a given metagenomic sample. Main premise is identification and analysis of ribosomal coding sequences which are considered to be indicators of presence of organisms. The solution works with RNA-seq data and is tested on a real dataset from an environmental sample

Keywords: metagenomics; bioinformatics; RNA-Seq

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