Nalazite se na CroRIS probnoj okolini. Ovdje evidentirani podaci neće biti pohranjeni u Informacijskom sustavu znanosti RH. Ako je ovo greška, CroRIS produkcijskoj okolini moguće je pristupi putem poveznice www.croris.hr
izvor podataka: crosbi !

Canine leptospirosis in Croatia – epizootiological and clinical features (CROSBI ID 625394)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Habuš, Josipa ; Štritof, Zrinka ; Mojčec, Vesna ; Milas, Zoran ; Perharić, Matko ; Martinković, Krešimir ; Starešina, Vilim ; Barbić, Ljubo ; Stevanović, Vladimir ; Hađina, Suzana et al. Canine leptospirosis in Croatia – epizootiological and clinical features // Program 2nd ELS meeting on leptospirosis and other rodent borne haemorrhagic fevers. Amsterdam, 2015. str. 39-39

Podaci o odgovornosti

Habuš, Josipa ; Štritof, Zrinka ; Mojčec, Vesna ; Milas, Zoran ; Perharić, Matko ; Martinković, Krešimir ; Starešina, Vilim ; Barbić, Ljubo ; Stevanović, Vladimir ; Hađina, Suzana ; Turk Nenad

engleski

Canine leptospirosis in Croatia – epizootiological and clinical features

Leptospirosis is a well-known zoonotic infection with worldwide distribution. Due to the increased incidence and number of outbreaks recorded during the past few years leptospirosis is classified as a (re)emerging zoonosis that presents a significant problem both in human and in veterinary public health. Additional concerns in veterinary medicine have been raised after recent reports from mainland Europe that indicated an altered epizootiological situation of canine leptospirosis. The aim of this study was to determine the incidence of canine leptospirosis, prevalence of the presumed infective serovars and to analyse main epidemiological and clinical features among clinically ill dogs in Croatia. A retrospective analysis of archive data obtained from NR Laboratory for leptospires and Clinic for infectious diseases was conducted. During a period of four years (January 2010 to October 2014), 311 canine sera were submitted to the Laboratory for leptospires, Faculty of Veterinary Medicine, University of Zagreb. Using a microscopic agglutination test (MAT) with cut-off point of 1:800, isolation procedures and/or PCR - 67 (21, 5%) positive animals were detected. The most prevalent presumed infective serovars, in decreasing order, were Pomona (33, 3%), Icterohaemorrhagiae (26, 7%), Grippotyphosa (21, 7%) and Bratislava (11, 7%) and infection was mainly detected in large breed male dogs from suburban and urban areas. Detailed clinical data of 27 dogs that were presented at the Clinic for Infectious diseases was additionally analysed. Most common presenting clinical signs included lethargy (89%), anorexia (85%), vomiting (70%), muscle weakness (63%), icterus (59%) and abdominal pain (59%). Major haematological and biochemical abnormalities were azotemia (93%), thrombocytopenia (70%), bilirubinemia (70%), anaemia (59%) and leukocytosis (56%). Although acute renal and hepatic failures were the most frequent clinical manifestations in dogs with leptospirosis a very high percentage of dogs with pulmonary involvement (41%) was also detected. Eight dogs were euthanized because of financial reasons connected with the high costs of intensive care while survival rate in treated animals was 63%. Negative outcome was mainly associated with leptospirosis pulmonary haemorrhagic syndrome (LPHS) and/or severe acute kidney injury (AKI). In this study, an increasing overall incidence of canine leptospirosis was detected, as well as increasing incidence of severe cases with high mortality due to severe AKI and pulmonary involvement. In addition, results showed that most infections were caused by serovars not covered by the currently used vaccines raising questions concerning its efficacy in preventing leptospirosis in dogs.

canine leptospirosis ; clinics ; epizootiology

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

nije evidentirano

Podaci o prilogu

39-39.

2015.

nije evidentirano

objavljeno

Podaci o matičnoj publikaciji

Program 2nd ELS meeting on leptospirosis and other rodent borne haemorrhagic fevers

Amsterdam:

Podaci o skupu

2nd ELS meeting on leptospirosis and other rodent borne haemorrhagic fevers

predavanje

16.04.2015-16.04.2015

Amsterdam, Nizozemska

Povezanost rada

Veterinarska medicina