An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3- acetyl-1, 3-bis(2-chloro-4-nitrophenyl)-1E- triazene (CROSBI ID 219464)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Molčanov, Krešimir ; Polanc, Slovenko ; Osmak, Maja ; Kojić-Prodić, Biserka
engleski
An axial chirality and disorder of positional isomers in a crystal of highly cytotoxic 3- acetyl-1, 3-bis(2-chloro-4-nitrophenyl)-1E- triazene
Biologically active 4-nitro-substituted 1, 3- diaryltriazene, a chemical analogue of 1, 3- bis(4'-amidinophenyl)-triazene-berenil®, belongs to the novel, chemically modified class of potent antitumor agents. Its structural characterization by X-ray analysis and 1H NMR spectroscopy is performed to determine molecular overall conformation in view of its possible interaction to DNA.
axial chirality; enantiomeric disorder; molecular structure; crystal structure
Posvećeno uspomeni na prof. dr. Jurija Brenčiča
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