Extended Eversion Carotid Endarterectomy: Computation of Hemodynamics (CROSBI ID 220426)
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Podaci o odgovornosti
Istvanić, Tomislav ; Vrselja, Zvonimir ; Brkić, Hrvoje ; Radić, Radivoje ; Lekšan, Igor ; Ćurić, Goran
engleski
Extended Eversion Carotid Endarterectomy: Computation of Hemodynamics
Stroke prevention includes surgery for significant stenosis of internal carotid artery. Consensus on a standard approach lacks and one alternative approach is eversion carotid endarterectomy (eCEA). In order to overcome disadvantages of eCEA, we developed extended eversion carotid endarterectomy (eeCEA). Aiming to investigate hemodynamics after different surgical approaches, we created computational fluid dynamics models of eeCEA and eCEA with included progressing lumen narrowing - representation of artery restenosis at the incision line. Methods: Blood flow velocities, volume flow rates and wall shear stress were established in carotid arteries from models of eCEA and eeCEA with included increasing groove (1, 1.5, 2 and 2.5 mm) at the ‘incision line’, under input pressure of 120 and 150 mmHg. Results: For the corresponding restenosis grade, models of eeCEA had a larger orifice towards internal carotid artery, lower blood flow velocities and higher volume flow rates in internal carotid artery, with lower volume flow rates in external carotid artery. Wall shear stress values in internal carotid artery of eeCEA models were lower than in eCEA models, later reaching the thrombotic range.
carotid endarterectomy; circulation; blood flow; wall shear stress; computational fluid dynamics
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Podaci o izdanju
Povezanost rada
Fizika, Temeljne medicinske znanosti, Biologija