engleski

Scaffolding using long error-prone reads

Scaffolding using long error-prone reads is very promising method for completion of draft genomes. Two methods were proposed for extending contigs in draft genomes. First one is based on local and global realignment of possible extension reads and second one uses POA algorithm for generating consensus sequence from these reads. Program was tested on two different types of long reads, PacBio and Oxford Nanopore Technologies. Project is implemented in C++ programming language.

Scaffolding; local and global realignment; POA; PacBio; Oxford Nanopore

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