engleski

RNA-seq mapper

RNA sequencing is a method for transcriptome analysis. Understanding the transcriptome is essential for various reasons such as interpreting the functional elements of the genome and undrestanding development of diseases, among many other use cases. This thesis presents a new RNA-seq spliced alignment algorithm, that uses finding the longest increasing subsequence in detecting splice sites and mapping spliced reads across exon junctions. Comparison between some of the state-of-the-art tools such as Tophat and BBMap are given.

RNA sequencing; hash; longest increasing subsequence; bioinformatics; genome; transcriptome

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