engleski

Increased calcium-independent lipoprotein phospholipase A2 but not protein S-100 in patients with schizophrenia

This study included 65 schiziphrenia patients and 70 controls. Schizophrenia was diagnosed according to DSM-IV-TR criteria. Clinical severity was determined by PANNS. PLA2 and S- 100 were assessed by ELISA method. PLA2 concentration werw higher in patients with schizophrenia, whereas protein S-100 concentzration werw not. Higher concentration of PLA2 were positive correlated with the duration of illnes and number of episodes, as determined by multivariate analysis. PLAA" might be considered a possible biochemical trait marker for schizophrenia.

schizophrenia ; calcium-independent phospholipase A2 ; protein S-100

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