Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3, 2-b]thiophene, Thieno[3, 2-b]furan and 1, 2-bis{;5-[2-(2-Thienyl)ethenyl]2-thienyl};ethene Series (CROSBI ID 94206)
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Podaci o odgovornosti
Pavličić, Davorka ; Dogan Koružnjak, Jasna ; Banić-Tomišić, Zrinka ; Karminski-Zamola, Grace
engleski
Synthesis of Some New bis-(p-Fluorophenyl)amides of the Thieno[3, 2-b]thiophene, Thieno[3, 2-b]furan and 1, 2-bis{;5-[2-(2-Thienyl)ethenyl]2-thienyl};ethene Series
Abstract: Three new heterocyclic substituted dianilides were prepared by multistep synthesis, namely 3-chloro-5-[1-(p-fluorophenylcarbamoyl)-2-(2-thienyl)ethenyl]thieno[3, 2-b]thiophene-2-carboxy-p-fluoroanilide (8), 1, 2-bis{;5-[2-(p-fluorophenylcarbamoyl)-2-(2-thienyl)-ethenyl]-2-thienyl};ethene (13) and 6-chloro-2-{;2-[3-chloro-2-(p-fluorophenyl-carbamoyl)-5-thieno[3, 2-b]thienyl]-2-ethoxycarbonylethenyl};thieno[3, 2-b]furan-5-carboxy-p-fluoroanilide (20). The prepared dianilides are of particular interest for their potential to serve as the planar heteroaromatic core of DNA intercalators or groove binders.
Amides; thieno[3; 2-b]thienyl-series; potential intercalators or groove binders.
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