Effect of propolis on liver functions and diet- induced hyperlipidemia in diet-induced obesity in mice (CROSBI ID 632902)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Landeka, I., Bertek, N., Jelić, S., Teparić, R., Oršolić, N., Đikić, D.
engleski
Effect of propolis on liver functions and diet- induced hyperlipidemia in diet-induced obesity in mice
One of the main environmental factors causing obesity in human is the intake of a high-fat diet. Obesity resulting from an accumulation of visceral adiposity is a primary cause of ˝metabolic syndrome˝ that is the combination of multiple cardiovascular risk factors, including visceral obesity, dyslipidemia, glucose intolerance, and hypertension. Propolis possesses many biological activities, such as antitumor, antioxidant, antimicrobial, anti- inflammatory, and immunomodulatory, among others. A diet-induced obesity animal model has been developed to investigate human obesity. Recent studies have reported that propolis prevented and mitigated diabetes and hypertension, but it remains unclear whether propolis effects the hyperlipidemia and liver functions. In this study we examined the effect of propolis on liver functions and hyperlipidemia induced in a high-fat diet induced obesity mouse model. The propolis extract, at dose of 50 mg/kg body weight/day, was given, by gauge, to mice for 30 days. At the end of the treatment, serum total triglyceride, cholesterol, high density lipoprotein (HDL), low density lipoprotein (LDL) and serum enzymes, such as aminotransferase (EC 2.6.1.2), phosphatase (EC 3.1.3.1), dehydrogenase (EC 1.1.1.27) were measured.
hyperlipidemia ; obesity ; propolis
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
119-119.
2010.
objavljeno
Podaci o matičnoj publikaciji
Zrinka Kovarik, Jadranka Varljen
Rijeka: Hrvatsko društvo za biokemiju i molekularnu biologiju (HDBMB)
Podaci o skupu
The secret life of biomolecules
predavanje
15.09.2010-18.09.2010
Opatija, Hrvatska