Stricter microbiological criteria are useful surrogate in estimating the prevalence of nontuberculous mycobacterial pulmonary disease in Croatia (CROSBI ID 634802)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Jakopovic, Marko ; Jankovic Makek, Mateja ; Sabol, Ivan ; Van Ingen, Jakko ; Zmak, Ljiljana ; Katalinic-Jankovic, Vera ; Ticac, Brigita ; Bulat-Kardum, Ljiljana ; Redzepi, Gzim ; Vranic-Ladavac, Mirna ; Samarzija, Miroslav
engleski
Stricter microbiological criteria are useful surrogate in estimating the prevalence of nontuberculous mycobacterial pulmonary disease in Croatia
Background: nontuberculous mycobacterial pulmonary disease (NTM-PD) is not reportable disease and its prevalence is difficult to assess. Aims and objectives: to assess the use of microbiological and stricter microbiological criteria in the estimation of the NTM-PD in Croatia. Methods: Retrospective analysis of the data from the Croatian national NTM registry. We included all patients with pulmonary NTM (without exclusion of any NTM species) isolated in the period from 2006 through 2013 that also had complete medical records data. Microbiological criteria of the American Thoracic Society (ATS) and stricter microbiological criteria (>3 positive sputum cultures or 1 bronchoscopic or lung biopsy culture + 1 positive sputum culture) were used to establish diagnosis of NTM-PD or NTM colonization, and then correlated to the whole ATS criteria. Results: We identified 368 patients with enough data for firm establishment of diagnosis with both criteria. By comparison of the rate of established NTM-PD diagnosis, we found good correlation between the ATS microbiological criteria and the whole ATS criteria (phi coefficient 0.66 ; 95% CI 0.61 to 0.72, p<0.0001). The strength of correlation increased when we compared stricter microbiological with full ATS criteria (phi coefficient 0.73 ; 95% CI 0.68 to 0.77, p<0.0001). Furthermore, use of ATS microbiological criteria had a positive predictive value (PPV) of NTM-PD of only 59.8%, while stricter microbiological criteria yielded a PPV of 93.3%. Conclusion: In our setting, stricter microbiological criteria may be used as surrogate criteria for laboratory based estimation of national prevalence of NTM-PD.
NTM; ATS criteria; pulmonary disease
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Podaci o prilogu
2015.
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objavljeno
Podaci o matičnoj publikaciji
The European respiratory journal
European Respiratory Society
0903-1936
Podaci o skupu
European Respiratory Society International Congress 2015
poster
26.09.2015-30.09.2015
Amsterdam, Nizozemska
Povezanost rada
Kliničke medicinske znanosti, Javno zdravstvo i zdravstvena zaštita