Cysteinyl-tRNA formation and prolyl-tRNA synthetase (CROSBI ID 94800)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Jacquin-Becker, Clarisse ; Ahel, Ivan ; Ambrogelly, Alexandre ; Ruan, Benfang ; Söll, Dieter ; Stathopoulos, Constantinos
engleski
Cysteinyl-tRNA formation and prolyl-tRNA synthetase
Aminoacyl-tRNA (AA-tRNA) formation is a key step in protein biosynthesis. This reaction is catalyzed with remarkable accuracy by the AA-tRNA synthetases, a family of 20 evolutionarily conserved enzymes. The lack of cysteinyl-tRNA (Cys-tRNA) synthetase in some archaea gave rise to the discovery of the archaeal prolyl-tRNA (Pro-tRNA) synthetase, an enzyme capable of synthesizing Pro-tRNA and Cys-tRNA. Here we review our current knowledge of this fascinating process.
aminoacyl-tRNA synthetase ; prolyl-tRNA synthetase ; amino acid activation ; tRNA ; translation
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