Wnt signaling is activated in human astrocytomas (CROSBI ID 643719)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Pećina-Šlaus, Nives ; Kafka, Anja ; Tomas, Davor ; Marković, Leon ; Varošanec, Ana Maria ; Bačić, Mateja ; Njirić, Niko
engleski
Wnt signaling is activated in human astrocytomas
Molecular and genetic landscapes of human astrocytic brain tumors still need elucidation. In the present study key players of Wnt signaling, beta-catenin (CTNNB1), TCF1 and LEF1, adenomatous polyposis coli (APC), AXIN1, SFRP3 and dishevelleds 1, 2 and 3 (DVL1, DVL2, DVL3) were investigated in human astrocytic tumors. Genetic changes were tested by PCR/loss of heterozygosity (LOH), microsatellite instability (MSI) and heteroduplex methods. Protein expressions were investigated by immunohistochemistry.
Wnt signaling ; human astrocytomas
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
2016.
objavljeno
Podaci o matičnoj publikaciji
Wnt Meeting 2016 EMBO Conference
Podaci o skupu
Wnt Meeting 2016 EMBO Conference
poster
14.09.2016-17.09.2016
Brno, Češka Republika