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Wnt signaling is activated in human astrocytomas (CROSBI ID 643719)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Pećina-Šlaus, Nives ; Kafka, Anja ; Tomas, Davor ; Marković, Leon ; Varošanec, Ana Maria ; Bačić, Mateja ; Njirić, Niko Wnt signaling is activated in human astrocytomas // Wnt Meeting 2016 EMBO Conference. 2016

Podaci o odgovornosti

Pećina-Šlaus, Nives ; Kafka, Anja ; Tomas, Davor ; Marković, Leon ; Varošanec, Ana Maria ; Bačić, Mateja ; Njirić, Niko

engleski

Wnt signaling is activated in human astrocytomas

Molecular and genetic landscapes of human astrocytic brain tumors still need elucidation. In the present study key players of Wnt signaling, beta-catenin (CTNNB1), TCF1 and LEF1, adenomatous polyposis coli (APC), AXIN1, SFRP3 and dishevelleds 1, 2 and 3 (DVL1, DVL2, DVL3) were investigated in human astrocytic tumors. Genetic changes were tested by PCR/loss of heterozygosity (LOH), microsatellite instability (MSI) and heteroduplex methods. Protein expressions were investigated by immunohistochemistry.

Wnt signaling ; human astrocytomas

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Podaci o prilogu

2016.

objavljeno

Podaci o matičnoj publikaciji

Wnt Meeting 2016 EMBO Conference

Podaci o skupu

Wnt Meeting 2016 EMBO Conference

poster

14.09.2016-17.09.2016

Brno, Češka Republika

Povezanost rada

Temeljne medicinske znanosti