engleski

Maternal and fetal complications and their association with gestational thrombocytopenia.

Objectives: Thrombocytopenia is defined as a platelet count of <150x109/L. It is a common hematologic abnormality during pregnancy. Evaluation and treatment of gestational thrombocytopenia can be expensive and invasive and can result in an adverse outcome. Our aim is to investigate the incidence of perinatal complications in pregnancies complicated with gestational thrombocytopenia and to determine if the severity of maternal gestational thrombocytopenia implicates unfavorable perinatal outcome. Material and methods: Over a period of three years we identified 50 patients with gestational thrombocytopenia: 38 patients had platelet count between 50-100x109/ L and were classified as having moderate thrombocytopenia and 12 women had platelet count <50x109/L and classified as having severe thrombocytopenia. 50 women with normal platelet count were observed as a control group. Maternal complications and neonatal outcomes were compared. Results: Neonatal thrombocytopenia occurred more often in pregnancies complicated with gestational thrombocytopenia (p=0.041). Thrombocytopenia in previous pregnancy seems to be an important predicting factor for the severity of thrombocytopenia in actual pregnancy (p=0.01). Conclusions: Gestational thrombocytopenia, even when severe, is not associated with adverse maternal or neonatal outcome. Moderate neonatal thrombocytopenia is more common in pregnancies complicated with severe gestational thrombocytopenia. Appearance of severe gestational thrombocytopenia is more frequent in patients with thrombocytopenia in previous pregnancy.

pregnancy ; complications ; tombocytopenia

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