engleski

BMPs in Inflammation

Bone morphogenetic proteins are regulators of embryonic development with multiple functions in adult organs and tissues. Here we summarize effects of BMPs outside the musculoskeletal system, focused on their role in inflammatory disorders, e.g., fibrosis, inflammatory bowel disease, anchylosing spondylitis, and rheumatoid arthritis. Additionally, we discuss the interplay between BMPs and vascular disorders leading to atherosclerosis and decipher the key role of BMP in iron metabolism.

Bone morphogenetic protein, Inflammatory bowel disease, Iron metabolism, Rheumatoid arthritis, Atherosclerosis

nije evidentirano