Implementation of Elastography Score and Strain Ratio in Combination with B-Mode Ultrasound Avoids Unnecessary Biopsies of Breast Lesions (CROSBI ID 240820)
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Podaci o odgovornosti
Bojanić, Kristina ; Katavić, Nataša ; Smolić, Martina ; Perić, Marija ; Kralik, Kristina ; Sikora, Miroslav ; Vidačić, Kristina ; Pacovski, Mirta ; Štimac, Damir ; Ivanac, Gordana
engleski
Implementation of Elastography Score and Strain Ratio in Combination with B-Mode Ultrasound Avoids Unnecessary Biopsies of Breast Lesions
The aim of this study was to evaluate whether the combination of B-mode ultrasound, elastography score (ES) and strain ratio (SR) improves diagnostic performance with respect to breast lesions. One hundred thirty lesions were prospectively evaluated by B-mode ultrasound and strain elastography, followed by fine- needle aspiration cytology/biopsy in 117 woman who were scheduled for regular breast BUS. The median ES (4.5 vs. 2.9, p < 0.001) and SR (4.9 vs. 2.3, p < 0.001) were significantly higher for malignant than for benign lesions. A sensitivity of 90.5% and specificity of 93.2% for the ES (cutoff point = 3.8) and a sensitivity of 87.5% and specificity of 87.6% for the SR (cutoff point = 3.5) were obtained. Elastography combined with B-mode ultrasound improved the specificity, accuracy and positive predictive value. Receiver operating characteristic curves yielded a higher value for the combined technique for diagnosis of breast lesions. Routine use of such a diagnostic algorithm could reduce the number of unnecessary biopsies. (E-mail: Bojanic.kristina@gmail.com) (C) 2016 The Authors. Published by Elsevier Inc. on behalf of World Federation for Ultrasound in Medicine & Biology.
Ultrasonography ; Strain elastography ; Elastography score ; Strain ratio ; Diagnostic accuracy ; Breast Imaging Reporting and Data System
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Podaci o izdanju
43 (4)
2017.
804-816
objavljeno
0301-5629
10.1016/j.ultrasmedbio.2016.11.019
Povezanost rada
Kliničke medicinske znanosti