engleski

Photocatalytic degradation of macrolide antibiotic azithromycin in aqueous sample

Azithromycin (AZI) is widely used macrolide antibiotic and its presence in waste water treatment plant (WWTP) influent is unequivocal. Many studies have shown that AZI is not being removed from the waste waters during the conventional waste water treatment. Therefore it can reach the environment and have possible adverse effect on the living organisms. It is of great importance to develop methods for waste water treatment that could completely remove pollutants such as AZI. Photocatalysis, one of advanced oxidation processes (AOP), has been presented as effective in removing organic pollutants such as pharmaceuticals in numerous studies. In this work aqueous samples of AZI have been subjected to photocatalytic degradation. Nanostructured sol-gel TiO2 was used as a catalyst but in the form of a film which makes the possible future implementation more applicable. Photocatalytic degradation was optimized in order to find the best experimental conditions for complete removal of AZI. Sample analysis was conducted on HPLC- MS/MS which was also used for monitoring of AZI degradation and determination of possible degradation products.

photocatalysis ; sol-gel TiO2 film ; azithromycin ; HPLC-MS/MS

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