engleski

Chemical composition, antioxidant and antibacterial activity of different extracts of poplar type propolis

Chemical composition, antioxidant activity and in vitro antibacterial activity of propolis from the central, continental part of Croatia were studied. Propolis hydro-ethanolic extracts (PHEE), prepared using three different methods and two solvent mixtures contained high amounts of flavonoids (27.96-28.11 % TIC) and aromatic acids (8.17–15.91 % TIC) and their esters (9.27-11.91 % TIC). The PHEE obtained in this study showed high antioxidant activity (DPPH IC50 values from 9.96- 19.95 µg/ml and FRAP 38.0-41.9 mM Fe2+/mg PHEE). Despite differences in composition, the PHEE samples exhibited significant antibacterial activities, affecting tested strains of Staphylococcus aures, Enterococcus faecalis, Escherichia coli and Moraxella catarrhalis. The use of different solvent ratio and extraction procedures selectively increases or decreases specific propolis components in the extract and could govern for its particular use in human and veterinary medicine.

propolis ; antioxidant activity ; antibacterial agents

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