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Association of Chronotype and Daytime Sleepiness with Myocardial Infarction. (CROSBI ID 661832)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Škrlec, Ivana ; Milić, Jakov ; Heffer, Marija ; Steiner, Robert ; Peterlin, Borut ; Wagner, Jasenka Association of Chronotype and Daytime Sleepiness with Myocardial Infarction. // 9th ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine. 2015

Podaci o odgovornosti

Škrlec, Ivana ; Milić, Jakov ; Heffer, Marija ; Steiner, Robert ; Peterlin, Borut ; Wagner, Jasenka

engleski

Association of Chronotype and Daytime Sleepiness with Myocardial Infarction.

Human physiological activities and diseases are under the control of circadian rhythm. The circadian rhythm is regulated by the suprachiasmatic nucleus (SCN) and multiple circadian clock genes. Sleep disorders are associated with vascular outcomes such as myocardial infarction (MI). Circadian rhythm is under the influence of lifestyle that can lead to MI. We conducted a cohort study of 200 patients who were hospitalized because MI and 200 healthy controls. Systematic information on the past and current medical history, plus the demographic variables was collected from each participant. Chronotype was assessed with the Morningness- Eveningness Questionnaire (MEQ) and daytime sleepiness with the Epworth Sleepiness Scale (ESS). Mean age of the study population was 64.1±12.8 years and 54.5% were males. No significant difference was found in MEQ scores among male patients versus male controls (59.3±6.4 vs. 58.3±7.6, p=0.909) and no significant difference in ESS score among two female groups (5.8±3.4 vs. 5.8±3.9, p=0.102). MEQ is associated with age in male patients (p=0.00026), but not in male controls and females. A significant association was found between ESS and dyslipidemia in patients (p=0.005) but not in the controls (p=0.228). ESS was associated with family anamneses of cardiovascular diseases in patients but not in the controls (p=0.008 vs. p=0.58). MEQ was associated with non-smoking in controls (p=0.0018). Risk factors for cardiovascular diseases, such as age, dyslipidemia, smoking, are associated with MEQ or ESS. There have been no studies to our knowledge looking specifically for differences in circadian rhythm among the MI patients and healthy controls.

cardiovascular diseases ; chronotype ; circadian rhythm ; myocardial infarction ; sleepiness

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Podaci o prilogu

MG 19

2015.

nije evidentirano

objavljeno

978-953-57695-1-4

Podaci o matičnoj publikaciji

9th ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine

Podaci o skupu

9th ISABS Conference on Forensic and Anthropologic Genetics and Mayo Clinic Lectures in Individualized Medicine

poster

22.06.2015-26.06.2015

Bol, Hrvatska

Povezanost rada

Biologija, Kliničke medicinske znanosti, Temeljne medicinske znanosti