Synthesis and complexation properties of novel glycoconjugated calix[4]arenes (CROSBI ID 663287)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Cindro, Nikola ; Požar, Josip ; Barišić, Dajana ; Bregović, Nikola ; Pičuljan, Katarina ; Tomaš, Renato ; Frkanec, Leo ; Tomišić, Vladislav
engleski
Synthesis and complexation properties of novel glycoconjugated calix[4]arenes
Calixarenes are a class of supramolecular cavitands that can be easily functionalized to give receptors for ionic and neutral species. Structural evolution of these compounds has led to more selective receptors with improved physico-chemical properties. Most of the synthesized calixarene ionic receptors are not sufficiently soluble in water which makes their use quite limited [1]. Water-soluble calixarenes usually own this property to the introduced easily-ionized sulfonic groups. In the scope of this work novel neutral and water- soluble ligands 1–3 (Figure 1) were designed and prepared, and their complexation with alkali-metal cations was investigated. Glucose was embedded in the structure as hydrophilic domain whereas secondary and tertiary amides served as cation-binding sites. The latter motifs were used since the calixarene derivatives comprising such groups were previously proven to form highly stable complexes [2]. Complexation reactions with alkali-metal cations were studied in water, methanol, and formamide thus giving insight into the solvation as well as intra- and intermolecular hydrogen bonds effects. Several techniques were used, such as UV spectrophotometry, isothermal titration calorimetry and NMR spectroscopy.
calixarene ; complexation ; glycoconjugate
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Podaci o prilogu
34-34.
2018.
objavljeno
Podaci o matičnoj publikaciji
Adriatic NMR Conference 2018 : Book of Abstracts
Bregović, Nikola ; Namjesnik, Danijel ; Novak, Predrag ; Pičuljan, Katarina
Zagreb: Kemijski odsjek Prirodoslovno-matematičkog fakulteta Sveučilišta u Zagrebu ; Geološki odsjek Prirodoslovno-matematičkog fakulteta Sveučilišta u Zagrebu
978-953-6076-42-0
Podaci o skupu
Adriatic NMR 2018
pozvano predavanje
15.06.2018-17.06.2018
Mali Ston, Hrvatska