Novel amidino substituted heterocyclic compounds of furan serie; synthesis and photochemical synthesis (CROSBI ID 485955)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Hranjec, Marijana ; Karminski-Zamola, Grace
engleski
Novel amidino substituted heterocyclic compounds of furan serie; synthesis and photochemical synthesis
The compounds in title are synthesized because of their potential antitumor activity. They could serve as intercalators in the reaction with DNA of maligmant cells [1]. In the reaction of condensation of methyl-E-3-(5-formyl-2-furyl)-2-phenylacrylate with corresponding 4-amidino substituted o-phenylenediamines [2], [3] , were prepared new subsituted benzimidazoles.The prepared benzimidazoles gave in the reaction of photodehydrocyclization [4] the next compounds: methyl-2-[(5-N-isopropylamidino)benzimidazolyl]naphtho[2,1-b]furan-5-carboxylatehydrochloride 1, methyl-2-{[5-N-(2-imidazolinyl)]benzimidazolyl}naphtho[2,1-b]furan-5-carboxylatehydrochloride 2 and methyl-2-[(5-N-morpholinylamidino)benzimidazolyl]naphtho[2,1-b]furan-5-carboxylatehydrochloride 3. All compounds were characterized by 1H and 13C NMR, IR and UV and by elementary analysis.
amidines; intercalators; photochemical dehydrocyclization
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Podaci o prilogu
40-x.
2003.
objavljeno
Podaci o matičnoj publikaciji
Zrnčević, Stanka
Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI) ; Hrvatsko kemijsko društvo
Podaci o skupu
XVIII.Hrvatski skup kemičara i kemijskih inženjera,
poster
16.02.2003-19.02.2003
Zagreb, Hrvatska