engleski

Angiogenesis in breast cancer

Angiogenesis is the formation of new blood vesels from the existing vascular network. It is a complex multistep process involving extracellular matrix remodeling, endothelial cell migration and proliferation, capillary differentiation, and anastomosis. It is very crucial for tumor progression and metastasizing. Intratumoral microvessel density is believed to reflect the degree of angiogenesis in carcinomas. Angiogenesis is also confirmed very important in many pre-neoplastic lesions.

angiogenesis; breast cancer

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