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Integrative functional genomic analysis of human brain development and neuropsychiatric risks (CROSBI ID 259552)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

(BrainSpan Consortium ; PsychENCODE Consortium ; PsychENCODE Developmental Subgroup) Li, Mingfeng ; Santpere, Gabriel ; Imamura Kawasawa, Yuka ; Evgrafov, Oleg V. ; Gulden, Forrest O. ; Pochareddy, Sirisha ; Sunkin, Susan M. ; Li, Zhen ; Shin, Yurae ; Zhu, Ying et al. Integrative functional genomic analysis of human brain development and neuropsychiatric risks // Science, 362 (2018), 6420; eaat7615, 13. doi: 10.1126/science.aat7615

Podaci o odgovornosti

Li, Mingfeng ; Santpere, Gabriel ; Imamura Kawasawa, Yuka ; Evgrafov, Oleg V. ; Gulden, Forrest O. ; Pochareddy, Sirisha ; Sunkin, Susan M. ; Li, Zhen ; Shin, Yurae ; Zhu, Ying ; Sousa, André M. M. ; Werling, Donna M. ; Kitchen, Robert R. ; Kang, Hyo Jung ; Pletikos, Mihovil ; Choi, Jinmyung ; Muchnik, Sydney ; Xu, Xuming ; Wang, Daifeng ; Lorente-Galdos, Belen ; Liu, Shuang ; Giusti-Rodríguez, Paola ; Won, Hyejung ; de Leeuw, Christiaan A. ; Pardiñas, Antonio F. ; Hu, Ming ; Jin, Fulai ; Li, Yun ; Owen, Michael J. ; O’Donovan, Michael C. ; Walters, James T. R. ; Posthuma, Danielle ; Reimers, Mark A. ; Levitt, Pat ; Weinberger, Daniel R. ; Hyde, Thomas M. ; Kleinman, Joel E. ; Geschwind, Daniel H. ; Hawrylycz, Michael J. ; State, Matthew W. ; Sanders, Stephan J. ; Sullivan, Patrick F. ; Gerstein, Mark B. ; Lein, Ed S. ; Knowles, James A. ; Šestan, Nenad

BrainSpan Consortium ; PsychENCODE Consortium ; PsychENCODE Developmental Subgroup

engleski

Integrative functional genomic analysis of human brain development and neuropsychiatric risks

The brain is responsible for cognition, behavior, and much of what makes us uniquely human. The development of the brain is a highly complex process, and this process is reliant on precise regulation of molecular and cellular events grounded in the spatiotemporal regulation of the transcriptome. Disruption of this regulation can lead to neuropsychiatric disorders.

transcriptome ; DNA methylation ; histone modifications

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Podaci o izdanju

362 (6420)

2018.

eaat7615

13

objavljeno

0036-8075

1095-9203

10.1126/science.aat7615

Povezanost rada

Kliničke medicinske znanosti

Poveznice
Indeksiranost