engleski

Optimization of ultrasound-assisted extraction of some bioactive compounds from tobacco waste

This is the first study on ultrasound-assisted extraction (UAE) of bioactive compounds from different types of tobacco industry waste (scrap, dust and midrib). The obtained results were compared with starting raw material (tobacco leaves) to see the changes in bioactive compounds during tobacco processing. Results suggested that tobacco waste extracts possess antioxidant activity and considerable amount of targeted bioactive compounds (phenolics and solanesol). Content of chlorogenic acid varied between 3.64 and 804.2 μg/mL, caffeic acid between 2.34 and 10.8 μg/mL, rutin between 11.56 and 93.7 μg/mL and solanesol between 294.9 and 598.9 μg/mL for waste and leaf extracts, respectively. There were noticeable differences between bioactive compounds content and antioxidant activity in extracts related to applied UAE conditions and used type of tobacco waste. Results shows that optimal UAE parameters obtained by response surface methodology (RSM) were different for each type of material, so process optimization proved to be necessary. Considering that tobacco waste is mostly discarded or not effectively utilized, the results clearly shows that tobacco waste could be used as a potential source of some bioactive compounds.

tobacco waste ; ultrasound-assisted extraction ; biocompounds ; process optimization

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