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izvor podataka: crosbi

Interactions of resveratrol with other phenolics and activity against food-borne pathogens (CROSBI ID 264548)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Skroza, Danijela ; Šimat, Vida ; Smole Možina, Sonja ; Katalinić, Višnja ; Boban, Nataša ; Generalić Mekinić, Ivana Interactions of resveratrol with other phenolics and activity against food-borne pathogens // Food science & nutrition, 7 (2019), 2312-2318. doi: 10.1002/fsn3.1073

Podaci o odgovornosti

Skroza, Danijela ; Šimat, Vida ; Smole Možina, Sonja ; Katalinić, Višnja ; Boban, Nataša ; Generalić Mekinić, Ivana

engleski

Interactions of resveratrol with other phenolics and activity against food-borne pathogens

The aim of this study was to investigate the antibacterial activity of individual phenolics, and their binary mixtures with resveratrol against selected food-borne pathogens. The antibacterial activity was quantified using the broth microdilution method by the determination of minimal inhibitory concentrations (MICs). Interactions between compounds in the binary phenolic mixtures were determined by calculating the fractional inhibitory concentration index (FICI). The influence of the number of OH groups in the phenols’ structure on their antibacterial activity was assessed by principal component analysis (PCA). The most effective compounds were flavone luteolin and flavonol rutin, while the weakest antimicrobial activity was observed for phenolic acid and flavan-3-ols (catechin and epicatechin). The synergistic effect (FICI≤0.5) of equimolar mixture of resveratrol with kaempferol was confirmed against S. aureus, B. cereus and E. coli, while the mixture of rutin with resveratrol proved synergistic only against S. aureus. The increasing concentrations of resveratrol in the mixtures with kaempferol and rutin resulted in a loss of synergism wich indicates that only selected phenolic mixtures, with optimal concentrations of their individual components, result in synergistic antibacterial activity. We didn´t find an association between total number of OH groups and antibacterial activity of either individual phenolics or their mixtures.

antimicrobial activity ; phenolics ; pathogens ; resveratrol ; phenolics interaction

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Podaci o izdanju

7

2019.

2312-2318

objavljeno

2048-7177

10.1002/fsn3.1073

Povezanost rada

Prehrambena tehnologija

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