Drenjančević-Perić, Ines; Durand, M.; Lombard J.H.
Dilations of middle cerebral arteries of Salt Sensitive rats are restored by receiving portions of Brown Norway chromosome 13 containing the BN renin allele
Abstracts of the 25th Conference of the European Society for Microcirculation ; u: Journal of Vascular Research 45 (2008) (S2) ; Cerebral microcirculation : Poster Session ; PCM3 / Koller, Akos (ed). - Karger , 2008. 161-161.
Part of a CC journal:
Conference of the European Society for Microcirculation : Integrating Vascular Biology and Medicine : Basic and Clinical Science (25 ; 2008)
Dahl SS rats middle cerebral arteries (MCA) exhibit an impaired relaxation in response to various dilator stimuli which is restored in MCA from overlapping congenic rat strains containing pieces of chromosome 13 containing renin gene from BN rats, This confirms the hypothesis that normal function of renin-angiotensin system is necessary for maintenance of normal vascular relaxation.
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Fundamental medical sciences
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