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Pregled bibliografske jedinice broj: 106478

Časopis

Autori: Brkljačić, Boris; Sučić, Mate; Božikov, Veljko; Hauser, M.; Hebrang, Andrija
Naslov: Treatment of autonomous and toxic thyroid adenomas by percutaneous ultrasound-guided ethanol injection.
Izvornik: Acta Radiologica (0284-1851) 42 (2001), 5; 447-481
Vrsta rada: članak
Ključne riječi: autonomous adenoma; thyroid; therapy; ethanol treatment; ultrasonography
Sažetak:
PURPOSE: To evaluate the feasibility and efficacy of US-guided percutaneous ethanol injection (PEI) in the treatment of autonomous and toxic thyroid adenomas. MATERIAL AND METHODS: PEI was performed in 42 patients with solitary, scintigraphically "hot" nodules (n=37) or toxic nodular goiter (n=5). The nodular volume ranged from 2.5 to 38 cm3 (mean volume, 20.7+/-14.1 cm3). Ethanol was injected using a free-hand technique, usually in multiple sessions, using color and power Doppler US guidance. Treatment success was evaluated following 3-4 months after PEI by scintigraphy, hormonal status, and US findings. RESULTS: The procedure was technically successful in 39 patients (93%). Three patients were lost to follow-up. Minor complications were pain (all patients), subcutaneous hematoma (n=6), and transitory dysphonia (n=1). A complete cure was achieved in 22 patients (52%), and a partial cure in 10 patients (24%). In 4 cases (9%), the result was unsatisfactory since only moderate hormonal remission was observed. A satisfactory results was thus achieved in 32/42 patients (76%). Significant nodular volume reduction was observed in all cases. Better results were observed in smaller nodules and in cases of autonomous adenomas. There were no cases of recurrent hyperthyreosis. CONCLUSION: US-guided PEI is an efficient and safe method in the treatment of autonomous thyroid nodules and it enables inactivation of nodules with minimal or transitory complications.
Projekt / tema: 044003, 108091
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kliničke medicinske znanosti,Javno zdravstvo i zdravstvena zaštita
URL cjelovitog teksta:
Google Scholar: Treatment of autonomous and toxic thyroid adenomas by percutaneous ultrasound-guided ethanol injection.



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