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Pregled bibliografske jedinice broj: 139048

Zbornik radova

Autori: Jarak, Ivana; Kralj, Marijeta; Pavelić, Krešimir; Karminski-Zamola, Grace
Naslov: Synthesis, photochemical synthesis and antitumor activity of new amidino substituted benzo[b]thieno quinolones
Izvornik: 13th European symposium on organic chemistry : programme & absrtacts / Šunjić, Vitomir (ur.). - Zagreb :
Skup: 13th European symposium on organic chemistry
Mjesto i datum: Dubrovnik - Cavtat, Hrvatska, 10.-15.09.2003.
Ključne riječi: benzo[b]thienoquinolones; amidines; photochemical dehydrohalogenation
Sažetak:
Quinolones have found many uses in medicinal and synthetic chemistry. Some of them possess interesting biological and pharmacological activities, such as antibacterial, antiasthmatic, antivirial and antitumor activity. New amidino- and bis- amidino- subsituted benzo[b]thienoquinolones 1-9 were prepared by multistep synthesis. Bis- and mono- amidino- supstituted anilides, obtained from corresponding cyano-anilides by Pinner reaction or by condensation of acyl-chlorides with p-amino-N(isopropyl)benzoamidine, were photochemicaly dehydrohalogenated in methanolic or aqueos solution to obtain quinolones. All prepared compounds were tested on their antitumor activities.
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Nema recenziju
Projekt / tema: 0098092, 0125005
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Kemija



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