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Pregled bibliografske jedinice broj: 139111

Zbornik radova

Autori: Ćaleta, Irena; Karminski-Zamola, Grace; Grdiša, Mira; Pavelić, Krešimir
Naslov: Novel cyano- and amidino-substituted styrylbenzothiazoles and their biological activity
Izvornik: 13th European simposium on organic chemistry : programme & abstracts / Šunjić, Vitomir (ur.). - Zagreb :
Skup: European simposium on organic chemistry (13 ; 2003)
Mjesto i datum: Dubrovnik - Cavtat, Hrvatska, 10.-15.09.2003.
Ključne riječi: styrylbenzothiazoles; amidines; biological activity
Sažetak:
A large number of benzothiazole derivatives are of considerable biological and chemical interest. Their pharmaceutical and agrochemical applications are of particular relevance. In order to find a new biologically active benzothiazole compounds we prepared in the multistep synthesis a serie of new styrylbenzothiazole compounds 1-9 starting from 6-cyano-2-methylbenzothiazole or 2-methylbenzothiazole and corresponding benzaldehydes. Cyano-derivatives of styrylbenzothiazoles 1-3 were converted by Pinner reaction into the corresponding amidine hydrochlorides 4-9. All styrylbenzothiazole compounds were tested on their antitumor activity. All compounds were characterized by means of IR, 1H- and 13C-NMR spectroscopy and elemental analysis.
Vrsta sudjelovanja: Poster
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Nema recenziju
Projekt / tema: 0125005
Izvorni jezik: ENG
Kategorija: Ostalo
Znanstvena područja:
Kemija



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