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Pregled bibliografske jedinice broj: 150627

Zbornik radova

Autori: Džijan, Snježana; Primorac, Dragan; Marcikić, Mladen; Lauc, Gordan
Naslov: Is likelihood ratio a sufficient tool to estimate confidence of a genetic match in a DNA-lead process of identification of war victims?
Izvornik: 13th International Meeting on Forensic Medicine Alpe-Adria-Pannonia, Abstract bookGraz :
Skup: 13th International Meeting on Forensic Medicine Alpe-Adria-Pannonia
Mjesto i datum: Graz, Austria, 21-22.05.2004.
Ključne riječi: forensics; DNA typing; human identity
Sažetak:
With the advance in typing tools and extraction procedures in the recent years, DNA analysis developed into amazingly powerful method for forensic analysis. For a number of years we are using autosomal STR typing as a tool to lead the process of identification of war victims in Croatia. Although DNA typing is very effective in finding possible identities of exhumed skeletal remains, this approach bears some risk of wrong identification. Here we report a case of a match between skeletal remains and mother, son and wife of a missing person with a cumulative likelihood ratio of nearly 2×109 that was shown to be a false match, since additional genetic testing (Y-STR and mitochondrial DNA) unequivocally excluded the proposed identity. Although we still use likelihood ratios as a main measure of the significance of a genetic match between exhumed skeletal remains and relatives of a missing person, in database matching the meaning of likelihood ratio is not as clear as in simple paternity cases and great care is needed to avoid wrong identification. In addition to DNA evidence we heavily relay on other types of evidence (such as the information about time, place and other conditions of disappearance), as well as anthropological and other "classical" forensic data as a "control mechanism" in the DNA-lead process.
Vrsta sudjelovanja: Pozvano
Vrsta prezentacije u zborniku: Sažetak
Vrsta recenzije: Međunarodna recenzija
Projekt / tema: 0006611, 0219041
Izvorni jezik: ENG
Kategorija: Znanstveni
Znanstvena područja:
Biologija,Temeljne medicinske znanosti



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