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Pregled bibliografske jedinice broj: 156188

Časopis

Autori: Pavelić, Jasminka; Križanac, Šimun; Kapitanović, Sanja; Pavelić, Ljubomir; Samaržija, Miroslav; Pavičić, Fadila; Spaventi, Šime; Jakopović, Marko; Herceg-Ivanovi, Zlata; Pavelić, Krešimir
Naslov: The consequences of insulin-like growth factors/receptors dysfunction in lung cancer
Izvornik: American journal of respiratory cell and molecular biology (1044-1549) 32 (2005); 65-71
Vrsta rada: članak
Ključne riječi: insulin-like growth factors; lung cancer
Sažetak:
The aim of this study was to investigate the consequences of IGFs/IGF receptors dysfunction in lung carcinomas. A correlation between increased expression (at mRNA and protein levels) for both, IGF 1 and IGF 1R, and decreased apoptosis rate was found in large cell carcinomas and adenocarcinomas. In both tumor types mutations in M6P/IGF 2R gene were also found. The findings suggest that disturbation of the IGFs/IGF receptors axis is involved in lung cancer formation.
Projekt / tema: 0101023, 0098108, 0098089, 0098106, 0098093, 0098092
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL cjelovitog teksta:
Google Scholar: The consequences of insulin-like growth factors/receptors dysfunction in lung cancer



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