Theoretical background and practical issues of stereological methods used in neurosciences (CROSBI ID 501571)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Šimić, Goran
engleski
Theoretical background and practical issues of stereological methods used in neurosciences
Any quantitative investigation of the human brain structural elements, e.g. determination of the total number of neurons/glial cells/synapses/receptors in a given brain region must first address the following questions: What is the best method for estimating the total number of these neural structures? What are the validity and the expected precision of the obtained data? What precision must the estimates attain with respect to the scientific question? The theorethical background of modern stereological methods which are used in neuroscientific research, such as optical and physical disector, optical fractionator and nucleator were given. The second part of the talk included practical issues and demonstrations of the above mentioned methods using the StereoInvestigator software (MicroBrightField, Williston, USA) and microscope-computer interface system.
stereology; optical disector; optical fractionator
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Podaci o prilogu
2003.
objavljeno
Podaci o matičnoj publikaciji
Podaci o skupu
First FENS/IBRO International Summer School "Development and Plasticity of the Human Cerebral Cortex"
pozvano predavanje
22.09.2003-24.09.2003
Zagreb, Hrvatska