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Theoretical background and practical issues of stereological methods used in neurosciences (CROSBI ID 501571)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija

Šimić, Goran Theoretical background and practical issues of stereological methods used in neurosciences. 2003

Podaci o odgovornosti

Šimić, Goran

engleski

Theoretical background and practical issues of stereological methods used in neurosciences

Any quantitative investigation of the human brain structural elements, e.g. determination of the total number of neurons/glial cells/synapses/receptors in a given brain region must first address the following questions: What is the best method for estimating the total number of these neural structures? What are the validity and the expected precision of the obtained data? What precision must the estimates attain with respect to the scientific question? The theorethical background of modern stereological methods which are used in neuroscientific research, such as optical and physical disector, optical fractionator and nucleator were given. The second part of the talk included practical issues and demonstrations of the above mentioned methods using the StereoInvestigator software (MicroBrightField, Williston, USA) and microscope-computer interface system.

stereology; optical disector; optical fractionator

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Podaci o prilogu

2003.

objavljeno

Podaci o matičnoj publikaciji

Podaci o skupu

First FENS/IBRO International Summer School "Development and Plasticity of the Human Cerebral Cortex"

pozvano predavanje

22.09.2003-24.09.2003

Zagreb, Hrvatska

Povezanost rada

Kliničke medicinske znanosti