crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 176035

Časopis

Autori: Boban Blagaić, Alenka; Blagaić, Vladimir; Romić, Željko; Sikirić, Predrag
Naslov: The influence of gastric pentadecapeptide BPC 157 on acute and chronic ethanol administration in mice.
( The influence of gastric pentadecapeptide BPC 157 on acute and chronic ethanol administration in mice. )
Izvornik: European journal of pharmacology (0014-2999) 499 (2004), 3; 285-290
Vrsta rada: članak
Ključne riječi: acute alcohol intoxication; withdrawal/chronic alcohol consumption; pentadecapeptide BPC 157; mice
( acute alcohol intoxication; withdrawal/chronic alcohol consumption; pentadecapeptide BPC 157; mice )
Sažetak:
The stable gastric pentadecapeptide BPC 157 (GEPPPGKPADDAGLV, M.W.1419), which was promising in inflammatory bowel disease (PL-10, PLD-116, PL-14736, Pliva) trials, protects against both acute and chronic alcohol-induced lesions in stomach and liver, but also, given peripherally, affects various centrally mediated disturbances. Now, in male NMRI mice BPC 157 (10 pg intraperitoneally, 10 ng and 10 microg, intraperitoneally or intragastrically) (i) strongly opposed acute alcohol (4 g/kg intraperitoneally) intoxication (i.e., quickly produced and sustained anesthesia, hypothermia, increased ethanol blood values, 25% fatality, 90-min assessment period) given before or after ethanol, and (ii) when given after abrupt cessation of ethanol (at 0 or 3 or 7 h withdrawal time), attenuated withdrawal (assessed through 24 hours) after 20%-alcohol drinking (7.6 g/kg) through 13 days, with provocation on the 14th day.
Projekt / tema: 0108196
Izvorni jezik: eng
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Temeljne medicinske znanosti
URL cjelovitog teksta:
Google Scholar: The influence of gastric pentadecapeptide BPC 157 on acute and chronic ethanol administration in mice.



  Verzija za printanje   za tiskati


upomoc
foot_4