crta
Hrvatska znanstvena Sekcija img
bibliografija
3 gif
 Naslovna
 O projektu
 FAQ
 Kontakt
4 gif
Pregledavanje radova
Jednostavno pretraživanje
Napredno pretraživanje
Skupni podaci
Upis novih radova
Upute
Ispravci prijavljenih radova
Ostale bibliografije
Slični projekti
 Bibliografske baze podataka

Pregled bibliografske jedinice broj: 186583

Časopis

Autori: Guha, A.; Mason, R.P.; Primorac, Dragan; Konopaske, G.; Miller, J.; Sinha, P.; Tulenko, T.N.; Hand, A.
Naslov: Interferon-induced growth arrest is mediated by membrane structual changes
Izvornik: Journal of interferon & cytokine research (1079-9907) 17 (1997), 11; 701-706
Vrsta rada: članak
Ključne riječi: IFN-gamma; messenger-RNA; antigens; cells; biosynthesis; modulation; surface; alters
Sažetak:
Interferon-gamma (IFN-gamma) is an immunomodulator shown to augment the expression of major histocompatibility (MHC) class I/class II antigens on the cell surface. In previous studies, we have demonstrated that the enhanced expression of these antigens on the cell surface is in part due to IFN-gamma-mediated abrogation of antigen shedding. In this study, me demonstrate that IFN-gamma induces structural changes in the cell membrane by altering the cholesterol/phospholipid ratio. Furthermore, such changes not only mediate enhanced expression of antigen on the cell surface but may drive the cells to growth arrest and apoptosis. These results were obtained by employing x-ray diffraction, electron microscopy, and DNA analysis.
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Current Contents Connect (CCC)
MEDLINE
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Puni text rada: 186583.1997_Journal_of_Interferon_and_Cytokine_research_Guha_Interferon-reduced.pdf (tekst priložen 28. Ožu. 2007. u 14:11 sati)
URL cjelovitog teksta:
Google Scholar: Interferon-induced growth arrest is mediated by membrane structual changes



  Verzija za printanje   za tiskati


upomoc
foot_4