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Pregled bibliografske jedinice broj: 190519

Časopis

Autori: Čikeš Čulić, Vedrana; Tičinović Kurir, Tina; Radić, Saša; Zemunik, Tatijana; Mesarić, Marko; Markotić, Anita
Naslov: Exposure to hypebaric pressure alters ganglioside expression in rat liver following partial hepatectomy
Izvornik: Periodicum biologorum (0031-5362) 107 (2005), 2; 67-69
Vrsta rada: članak
Ključne riječi: hyperbaric pressure; partial hepatectomy; gangliosides
Sažetak:
Remnant liver after partial hepatectomy (PH) demands an increased amount of oxygen to restore hepatic energy. Modulation of the ganglioside content of hepatocyte plasma membrane could provide a mean for upregulating cellular responsiveness to a variety of factors. Rat liver gangliosides were analysed by high perfomance thin layer chromatography (HPTLC) followed with immunostaining 54 h after PH. Non-operated and three different groups of operated rats were studied according to the hausing conditions before or after operation: recovering under normal ambient conditions after operation (1), treating with hyperbaric pressure before operation and recovering under normal ambient conditions (2 or preHB), and recovering under hyperbaric pressure after operation (3 or postHB). Liver of preHB group showed the highest expression of ganglioside GD1a, a marker of a peculiar transition phase of liver regeneration. Same animals showed enhanced expression of the several gangliosides: GM2, GM1a, GD1b, GT1b, GalNAcGM1b, nLc4, nLc6 and nLc8. Since galactosyl- and N-acetylgalactosaminyltransferase catalyse final step of synthesys of GM2, GM1a, GD1b, GalNAcGM1b, nLc4, nLc6, and nLc8, our results point at possible role of galactosyl- and N-acetylgalactosaminyltransferase in regulation of the liver growth after PH.
Projekt / tema: 0216011, 0216013
Izvorni jezik: ENG
Rad je indeksiran u
bazama podataka:
Scopus
SCI-EXP, SSCI i/ili A&HCI
Science Citation Index Expanded (SCI-EXP) (sastavni dio Web of Science Core Collectiona)
Kategorija: Znanstveni
Znanstvena područja:
Kemija,Temeljne medicinske znanosti
Puni text rada: 190519.hdf_Markotic_et_al_ms.doc
URL cjelovitog teksta:
Google Scholar: Exposure to hypebaric pressure alters ganglioside expression in rat liver following partial hepatectomy
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