engleski

Cancer micrometastasis detection and destruction using antibody coated superparamagnetic nanoparticles induced hyperthermia, current state of the art and perspectives of applications in the metastatic cancer

Bimedical applications of nanotechnology, such as early in vivo metastatic disease detection and specific cell destruction, were documneted, using small sized supermagnetic coated particles with specific antibodies. Antibody coated nanoparticles can be used as contrast markers in magnetic resonance imaging (MRI) of targeted cells and at the same time in temeprature induced specific, in situ destruction of these cells, using external alternative magnetic field application. Oure experimental results corroborate this hypothesis. Combined diagnosis with treatments many considerable applications of nanotechnology in biomedicine could be performed depending on availability of appropiate antibodies.

micrometastasis; nanoparticles; cancer; MRI

Sudjelovanje kao Chairman nanomedicine na "Shanghai International Conference on Physiological Biophysics" November 9-13 2004